Zika, a mosquito-borne virus that was first discovered in 1947 in Uganda, has resurged, spreading rapidly across the world. There were only thirteen countries with evidence of local Zika infections in or before 2015. Since then, more than seventy countries and territories have reported evidence of Zika virus transmission. In February 2016, the World Health Organization declared Zika a public health emergency of international concern (PHEIC). Thus far, most cases have been clustered in Latin America (with Brazil reporting the largest number of cases), but they are increasingly being identified in North America, Asia, Africa, and the South Pacific. On September 10, fourteen new cases of locally transmitted Zika were confirmed by Singapore’s health authorities, bringing the total number of confirmed cases to 318, making the city-state house the largest cluster of the disease in Asia.